St Mary's CofE Primary School, Penzance is a primary school based in Penzance under the Cornwall local authority.

St Mary's CofE Primary School, Penzance caters for mixed pupils from 3 to 11 years. With 139 pupils enrolled and a capacity of 190, the school provides a structured and balanced curriculum aligned with national expectations.

The most recent Ofsted inspection, published on 14 March 2023, rated the school Outstanding. Inspectors highlighted the overall quality of education and the strong relationships between staff and pupils.